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Weight management can be challenging with RA

Generally, it is recognized that there are three distinct paracellular epithelial permeability pathways: leak and pore pathways, both regulated by TJs, which define intestinal permeability under condition of homeostasis

Real-world pharmacovigilance data is broadly consistent with these findings, though isolated case reports exist for both medications

It is important to note that while topiramate and atogepant have weight loss as a side effect, they are not FDAindicated/approved for weight loss and should not be used solely for weight management

PROGRAM OUTLINE What's included in a monthly plan