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Require a clinical evaluation before prescription

We have very good evidence that the [ability] of these drugs to reduce heart attacks and strokes [doesnt] require weight loss

There is no one-size-fits-all answer
Managing kidney disease requires a delicate balance: enough immunosuppression to control inflammation, but not so much that infection risk becomes unacceptable

Review of adult data In adults, multiple studies have demonstrated that bariatric surgery results in substantial improvements in MASLD and MASH