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Individual patient factorsincluding the reason for cholecystectomy, time since surgery, and presence of ongoing digestive symptomsshould inform treatment decisions
Clinical outcomes: Significant average weight loss, improved A1C, favorable effects on some cardiovascular risk markers in appropriate patients
Preclinical studies have found that Ex-4 significantly upregulates Sirt3 expression in glioblastoma by activating the GLP-1R, which subsequently inhibits the growth, migration, invasion, and epithelial-mesenchymal transition of glioma cells [87]
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10.1038/s41433-021-01741-5 [DOI] [PMC free article] [PubMed] [Google Scholar] 91.Cigrovski Berkovic M, Strollo F
