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Activating these receptors improves how your body handles blood sugar, reduces inflammation in your gut lining, and may even protect heart function

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Most of the weight tends to return after stopping (Wilding 2022)

Verdich C, Toubro S, Buemann B, Lysgard Madsen J, Juul Holst J, Astrup A

NICE guidelines (NG28) support their use in specific clinical scenarios, particularly for patients with a BMI 30 kg/m (or 27 kg/m in certain ethnic groups) when HbA1c targets are not met or when weight reduction would provide significant health benefits