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Description
GH secretion follows a circadian rhythm: the largest pulse occurs 6090 minutes after sleep onset, driven by declining somatostatin (GH's inhibitory hormone) and rising GHRH
Investigational Metabolic Research
Orforglipron is a daily oral pill that can improve adherence for patients who have needle aversion or want an easy-to-use option
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While both companies that have a monopoly on these drugs (Novo Nordisk and Eli Lilly) have enjoyed an incredible run-up from 2020 to 2024, both are now in a drawdown
