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Improved systemic inflammatory status could represent a significant cofactor in reducing the risk of NAFLD progression and HCC development, as well as a crucial determinant of the cardiovascular protection exerted by GLP-1 RAs [139]

Study Strengths and Limitations Our study has several strengths

Available from: Hamed K, Alosaimi MN, Ali BA, Alghamdi A, Alkhashi T, Alkhaldi SS, et al

These formulary updates are one component of CVS Healths ongoing efforts to address rising prescription drug costs and improve access to affordable medications for the millions of Americans it serves.

Evidence from a multicenter, long-term cardiovascular outcome trial demonstrated that GLP-1RAs reduce mortality associated with cardiovascular disease and confer protective effects by decreasing the incidence of myocardial infarction and nonfatal stroke.104 GLP-1RAs have been shown to enhance endothelial cell function through anti-inflammatory and vasodilatory mechanisms