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As previously shown in non-obese mice, NHPs 28 , and humans (accompanying paper), the -MSTN/-ActA group also had significant increases in lean mass (Fig

Conversely, although off-label use of GLP-1 RA for overweight and obesity cannot be excluded, such use was likely limited in the present study given existing prescription guidelines and regulatory vigilance

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Evidence Must Precede Adoption For any delivery system to be considered viable, it must demonstrate three things in human studies: Measurable absorption into circulation Engagement with the intended biological receptor Meaningful, reproducible outcomes

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