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Description
Studies indicate reduced risk of major cardiovascular events in adults with obesity and established heart disease
doi: 10.1056/NEJMoa2107519
The FTO gene (rs9939609) and MC4R gene (rs17782313) variants also affect baseline metabolic rate and appetite regulation, potentially modulating how severely side effects manifest and how quickly appetite suppression becomes tolerable
The goal is preventing severe nausea that makes you quit
Endocrinology 140: 1132-1140, 1999
