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Key Points Ozempic (semaglutide) commonly causes constipation by slowing down your digestive system, with higher rates at weight-loss doses Research shows constipation from Ozempic typically lasts longer (about 7 weeks) than other side effects like nausea Simple strategies like staying properly hydrated, gradually increasing fiber, and staying active can help manage constipation while on Ozempic If you've started Ozempic for diabetes or weight loss and suddenly found yourself dealing with constipation, theres no reason to be concerned

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5 With the addition of GLP-1 to the skin-derived cells, phosphorylation of ERK1/2 was noted and consistent with active protein kinase/phosphatase signaling

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