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Tambin se ha comprobado que los agonistas de los receptores GLP-1 tienen efectos beneficiosos en la presin arterial, en el colesterol y en la mejora del control glicmico en pacientes con diabetes 2, pero no se constataron diferencias significativas en las enzimas hepticas

PKA induction from native GLP-1 phosphorylates a key serine residue in NOS [40]

Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists

Albeit, in this regard, further quantitative studies determining drug concentrations in plasma and brain are required, and evaluation of plasma and cerebrospinal fluid levels in human studies from ongoing clinical trials would prove valuable

J Clin Endocrinol Metab 98:25532561