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Researchers also highlighted that all included studies had either some concerns or a high risk of bias, often due to issues such as missing data or participant unblinding
The problem is when we start looking to public insurance programs to cover them
doi: 10.1016/s0026-0495(99)90232-9

Weight typically regains (about two-thirds of lost weight within a year)
Their profound effect on weight loss has resulted in widespread use of these medicines for treating obesity
