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Miura T, Noma H, Furukawa TA, Mitsuyasu H, Tanaka S, Stockton S, et al

Semaglutide is the active ingredient in Ozempic and Wegovy
Simultaneously, GLP-1 interacts with afferent vagal fibers that transmit the signal to the brainstem and the hypothalamus
The historical tendency to equate pleiotropy with risk rather than opportunity appears increasingly outdated in light of contemporary successes with multi-agonist and network-based therapies
Frias et al., Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial, Lancet Lond
