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Dopaminergic pathways (NAc, SNc, VTA) influence reward-driven eating, aiding adherence to dietary changes 46,47

[DOI] [PMC free article] [PubMed] [Google Scholar] 146.Fontes A., Alemany-Pages M., Oliveira P.J., Ramalho-Santos J., Zischka H., Azul A.M

This in turn leads to excessive storage of underutilized glucose in the liver (glycogenesis), the potential for developing fatty liver (ie, nonalcoholic steatohepatitis), and conversion of excess carbohydrates to fatty acids and triglycerides, with subsequent storage in adipose tissue

Diet soda can frustrate your weight loss efforts and diabetes management by increasing your appetite, and it may also increase the long-term risk of conditions such as kidney disease and heart disease

Moreover, the localization of these proteins to specific cellular compartments, their post-translational modifications, and their interactions with other proteins or cellular structures further impact their activity and the overall cellular response