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Since their inception in the commercial market in the mid-twentieth century, sulfonylureas (SUs) have remained a therapeutic option in the management of type 2 diabetes (T2D)

Now the challenge was to find a small molecule that also fits that pocket

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A rheumatologist explains the 2025 UCLA and ACR research on GLP-1 medications, inflammation, microdosing, and heart risk in RA.

Peptide agonists of the glucagon-like peptide-1 receptor (GLP-1R) have revolutionized diabetes therapy, but their use has been limited by the requirement for injection