glp 1 agonist in heart failure GLP-1 Receptor Agonists Management Glucagon-like peptide 1(GLP-1) receptor agonists

Adverse effects GLP-1RAs are generally well tolerated, but with a common set of side effects, typically affecting the gastrointestinal system

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Appetite Suppression (Central Nervous System) GLP-1 RAs can cross the blood-brain barrier or act on circumventricular organs to target specific brain regions, including the hypothalamus, hindbrain, and mesolimbic reward system (Zheng et al., 2024)

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cAMP = cyclic AMP