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We have pulled one lever (weve lost the weight), but that means there is an equal and opposite reaction on the other side until the levers are balanced again (why did we gain it to begin with?)

Currently, the FDA has approved three GLP-1 RAs for obesity treatment: liraglutide, semaglutide and tirzepatide

For overweight women with PCOS, reducing body weight is the best way to improve fertility and pregnancy outcomes [24]

Cell Survival and Proliferation: GLP-1 signaling activates the PI3K/Akt pathway, which promotes -cell survival by inhibiting apoptotic signals (such as caspase activation) and enhancing proliferation (Zheng et al., 2024)

Limited recent data exist on prescribing patterns and patient characteristics for GLP-1 RA medications, whether used as anti-diabetic medication (ADM) for patients with type 2 diabetes (T2D) and/or used as an anti-obesity medication ( for patients with overweight or obesity