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Background Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, is available in the form of two FDA-approved injection products, Wegovy and Ozempic

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In people with normal glucose tolerance, the early (30- or 60-minute) rise in plasma glucose following a 75 g oral glucose challenge is directly proportional to the rate of emptying, while this relationship is reversed at 120 minutes (the time point conventionally used in the diagnosis of diabetes)