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The potential neuroprotective properties of GLP-1R agonists have also been demonstrated in clinical trials, with Novo Nordisk currently running a phase III clinical trial of oral semaglutide as a potential treatment option for Alzheimers disease in the announced EVOKE trial program (NCT04777409, NCT04777396)

Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines

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J Korean Thyroid Assoc 2014;7:7-39.Article 93

[13] [14] The once-weekly subcutaneous dosing schedule and careful dose titration can help mitigate gastrointestinal symptoms
