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This accumulation pattern was used in all clinical trials demonstrating weight loss and metabolic benefits
In the STEP 1 trial published in Diabetes, Obesity, and Metabolism , participants who paired weekly semaglutide for weight loss with a structured lifestyle intervention regained an average of two-thirds of the weight theyd lost within one year after stopping both
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Besides Kentucky, other Southeastern states with high rates of GLP-1 use include Alabama (1.7%), West Virginia (1.7%), and Georgia (1.6%)
