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The 5:1 GIP: GLP-1 binding ratio of tirzepatide exemplifies one strategy
Obesity, currently defined as a body mass index (BMI) of 30 kg/m 2 or greater, affects 800 million people worldwide [1]
As a result, there is an enormous interest in developing myostatin inhibitors to preserve muscle mass in patients receiving GLP-1 drugs
doi:10.4093/dmj.2025.0242 3
