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Side Effects Wegovy Side Effects The most commonly reported side effects in clinical trials were: Nausea (reported in 44% of patients) Diarrhoea (reported in 30% of patients) Vomiting (reported in 24% of patients) Constipation (reported in 24% of patients) Other side effects included abdominal pain, headache, fatigue, and dizziness

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Stimulation of adenosine A2B receptor inhibits endothelin-1-induced cardiac fibroblast proliferation and alpha-smooth muscle actin synthesis through the cAMP/Epac/PI3K/Akt-signaling pathway