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Description

Logistic regression models to evaluate the association between R group and each glycaemic parameter were performed and receiver operating characteristic (ROC) curves were drawn

For the primary analysis, aITCs were based on results for the efficacy estimand (referred to as the trial product estimand in SUSTAIN FORTE), which was defined as the treatment effect among all patients who underwent randomization and received at least one dose of the study medication, excluding the data after the start of rescue therapy (for persistent hyperglycaemia) or study drug discontinuation

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MEASUREMENTS: Energy expenditure and substrate oxidations were measured before and for 4 h after standard breakfast (20% of calculated daily energy requirements, 50% of energy from carbohydrates, 37% of energy from fat and 13% of energy from protein) using a ventilated hood system