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The first cohort included 6696 patients who started GLP-1 receptor agonists and added on SGLT-2 inhibitors, and the second included 8942 patients who started SGLT-2 inhibitors and added on GLP-1 receptor agonists

The glucagon-like peptide-1 receptor (GLP-1R) is a class B G proteincoupled receptor that regulates glucose homeostasis by promoting cAMP production and insulin secretion in pancreatic -cells

As the GLP-1 economy cools, CVS Ventures leads a $25 million round in Knownwell betting on physician-led obesity care and payer-backed innovation.

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In this article, we review the latest research to highlight when these medications might offer the greatest benefit for patients with substance use disorders.