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doi: 10.1093/ageing/afy169

The tissue-specific activities are regulated by the interaction of many signalling pathways, notably the cAMP/PKA and PI3K/Akt pathways, which together mediate GLP-1's metabolic and protective effects

AstraZeneca Boehringer Ingelheim International GmbH Genentech, Inc

References 1 MuscogiuriGCignarelliAGiorginoFProdramFSantiDTirabassiGet al

Navigation of dietary preferences and intakes GLP-1s meaningfully impact total energy intake and food preferences through multiple mechanismsan active area of investigationincluding peripherally in the gut, centrally in multiple brain regions, and through diet-microbiome-brain interactions [133]
