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Evaluation: Body fat (DXA scanning) Lean mass Insulin sensitivity Energy expenditure What they found: The combination showed an additive effect on fat reduction vs monotherapy AOD-9604 partially protected lean mass during GLP-1-induced weight reduction Increased energy expenditure in combination (~3 % vs GLP-1 alone) No new safety signals Why it matters: It validates the concept of combination , the idea that AOD-9604 may not work on its own, but can add value in combination with incretin agonists

Ruby Memorial Hospital is a research hub in REVEAL-1, a study exploring whether a minimally invasive endoscopic procedure could help patients maintain their weight loss after they stop taking GLP-1s

Semaglutide is a GLP-1 receptor agonist that was originally developed to treat type 2 diabetes

A diet filled with colorful fruits, vegetables and a wide range of dietary fibers supports a healthy gut and your bodys natural production of GLP-1

Eat a small, easily digestible meal 60-90 minutes before training -- not a full meal, but something with protein and carbs that will not sit heavy