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About 80% of participants in tirzepatides clinical trial reported a side effect, most often nausea, diarrhea, and constipation, and 4% to 7% of people had to stop taking it due to side effects, compared with about 3% of people taking a placebo
For example, Mounjaro contains the active ingredient tirzepatide, a dual agonist that acts on GLP-1 and GIP
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