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doi: 10.1056/NEJMoa2206038 201 ArmstrongMJGauntPAithalGPBartonDHullDParkerRet al
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Early clinical trial data, most notably from the Phase 2 trial published in the New England Journal of Medicine (Jastreboff et al., 2023), demonstrated that retatrutide produced substantial reductions in body weight up to approximately 24% over 48 weeks at the highest doses studied
This combination of effects is what makes GLP-1 therapies useful for blood sugar control and weight loss, and may also explain why researchers are now exploring their impact in other areas
