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In these studies, obese patients taking tesofensine lost more weight than those who took a placebo, including significant reductions in visceral fat

As many patients receiving GLP-1 RAs are treated with combination regimens, attribution of observed microbial shifts exclusively to GLP-1 RAs should be approached cautiously

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In the Morris Water Maze test, untreated diabetic rats needed more time to find the hidden platform, suggesting impaired spatial learning performance

ii) scheduled to undergo or having undergone first-line ICI therapy (either as monotherapy or in combination)