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To address the question of whether the cardioprotective actions of GLP-1(2836) require a functional transmembrane GLP-1R, we repeated these experiments using hearts isolated from mice with genetic deletion of 2 exons of the Glp1r gene (26)

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ESSENTIALLY, WHAT WERE DOING IS WERE KIND OF BURNING OFF THE TOP LAYER OF THAT MUCOSA IN THE SMALL BOWEL SO THAT IT GROWS BACK NORMALLY

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