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EECs contain peptides (also sometimes termed hormones) in secretory granules, and upon chemical, mechanical, or neural stimulation, an influx of intracellular calcium stimulates the secretion of gut peptides through the basolateral membrane and into the extracellular space 17

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This approval could continue to unlock eHealth options for Wegovy in Europe, providing new ways to make delivery easier and potentially cheaper for partners

As the key technology behind #Rybelsus (oral #semaglutide), SNAC temporarily increases the local gastric pH, protecting GLP-1 from enzymatic degradation and enabling direct absorption through the gastric lining into systemic circulation