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This can be a sign of pancreatitis, a rare but serious side effect
You feel uncomfortably full, bloated, or pressured in your lower belly

[Accessed on 11 June 2026] Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): a randomised, double-blind, placebo-controlled, phase 3 trial (2023)
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