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The median follow-up for radiographic PFS was 17.5 months in the talazoparib group and 16.8 months in the placebo group.[85,86][Level of evidence B1] Grade 3 or higher adverse events occurred in 68% of patients in the talazoparib-with-enzalutamide group and 40% of patients in the placebo-with-enzalutamide group
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