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JAMA 334 , 12311234 (2025)
They play a very important role in psoriasis patients with type 2 diabetes, and the administration of a GLP-1 analogue improved the psoriasis severity by decreasing the dermal T-cell number and IL-17 expression (41)
The strongest evidence we currently have relates to gut motility, not IBS specifically
All the GLPs can cause gastrointestinal side effects, from tummy upset, constipation, nausea to diarrhea
Semaglutide targets the GLP-1 receptor only, while Tirzepatide targets both GLP-1 and GIP receptors making it a dual-action medication
