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Because insulin resistance is so common among Cysters, your body might not produce enough GLP-1 to respond to it well

However, when semaglutide was studied at higher doses for obesity under the Wegovy brand, a different picture emerged

GLP-1 RAs can also cause bloating and burping, partly from delayed stomach emptying (food sits and ferments longer in the gut) and perhaps changes in gut bacteria

They ran four parallel studies based on different patient profiles: ADM trial: Patients with type 2 diabetes (T2D), comparing newer GLP-1 RAs to older GLP-1 RAs, sulfonylureas, and other anti-diabetic medications (ADMs)

Patients living with obesity and PCOS often present significant visceral fat accumulation, resulting in elevated free fatty acid release that contributes to increased hepatic total cholesterol synthesis and dyslipidemia, manifesting as elevated triglyceride, total cholesterol, and LDL-C levels