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References Centers for Disease Control and Prevention (Mar 2022)

Another may need a higher dose for glucose control

Notably, Trulicity carries a higher risk of low blood sugar (hypoglycemia) when used with insulin or sulfonylureas (up to 20%), while Zepbound shows lower hypoglycemia rates (~5%)

The drugs, which work by suppressing appetite, are not suitable for everyone and can have severe side effects

These symptoms are usually most intense during the first few weeks of treatment or immediately following a dose increase
