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Research indicates that GLP-1s may have beneficial effects in those with knee osteoarthritis, including reduced pain and fewer joint replacements by reducing weight and inflammation

Supplements to avoid or use with caution on GLP-1 therapy Not every supplement is helpful during GLP-1 treatment

Semaglutide should be discontinued at least two months before planned conception

Diabetes Metab 101508 Schirra J, Nicolaus M, Woerle HJ, Struckmeier C, Katschinski M, Gke B (2009) GLP-1 regulates gastroduodenal motility involving cholinergic pathways

First, these patients frequently present with endocrinemetabolic disorders such as diabetes or obesity, making perioperative glycemic regulation and metabolic optimization critical