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Description
Its discernment
Several mechanisms have been proposed to explain the association between diabetes and cancer, such as hyperglycemia, hyperinsulinemia, increased bioactivity of insulin-like growth factor 1, oxidative stress, sex hormone dysregulation, and chronic inflammation [37]

Since GLP-1 activity gradually declines as a function of the distance from the DTC 38,39 , we focused on nuclei located within 5 cell diameters from the DTC, where activity is strongest (Fig
This trial followed the Consolidated Standards of Reporting Trials (CONSORT) reporting guideline

Nakatani Y, Kaneto H, Kawamori D, et al