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Diabetes Metab Res Rev (2016) 32(8):77690
As per FDA approval in 2021, it's indicated for chronic weight management in adults with obesity or overweight with at least one weight-related condition such as high blood pressure, type 2 diabetes mellitus or high cholesterol (hyperlipidemia)
Aetna's coverage policies typically restrict semaglutide to members with type 2 diabetes or documented metabolic conditions, often denying weight-loss-only claims

Significant and clinically meaningful dose-dependent HbA1c reductions were specifically observed in patients taking 4mg-12mg of Retatrutide, and the same held true for weight loss