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Severe gastrointestinal symptoms could also lead to dehydration, which may increase the risk of methotrexate toxicity by affecting renal function

While discomfort is common, it is usually temporary and manageable with the right approach

Understanding the hurdles the blood-brain barrier presents are numerous but generally limited by blood-brain barrier permeability

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As a result FDA paused the end of the shortage and announced it was reconsidering its position
