glp 1 is Glucagon-like peptide-1 Understanding GLP-1 medications
Description
The GLP-1 peptide (a short chain of amino acids) is secreted by cells in the small intestine, but it is also synthesized in the brain
GLP-1 is a substrate with a high affinity for DPP-4 (direct target)
Diabetes Care 2017
Collectively, all GLP-1 receptor agonists, including native GLP-1, peptides, and small molecule GLP-1 receptor agonists, stabilize the binding pocket of the GLP-1 receptor in a similar fashion, which induces the TM helices 6 kink, a distinctive feature of the active state of the class B1 GPCR
Still, you have to take them diligently if you want to see results
