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[DOI] [PubMed] [Google Scholar] 217

Why it matters: Early, weight-independent impact could shift paradigms from wait 72 weeks for benefit to real-world protection within months
Tirzepatide (Mounjaro/Zepbound) has demonstrated greater weight loss than semaglutide in clinical trials, with participants losing up to 22.5% of body weight

( 10.1038/s41467-020-14309-w) [DOI] [PMC free article] [PubMed] [Google Scholar] Baggio LL & Drucker DJ

Serious but rare side effects can include pancreatitis, gallbladder issues, or kidney problems due to dehydration
