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Description
The bacterium maintains mucosal homeostasis via specialized mucinolytic enzymes while secreting functionally diverse components including SCFAs, outer membrane proteins (notably Amuc_1100), and extracellular vesicles (EVs)

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Methods SURMOUNT-2 participants were randomly assigned (1:1:1) to receive either tirzepatide 10 mg (n=312), tirzepatide 15 mg (n=311), or placebo (n=315) for 72 weeks as an adjunct to diet and exercise

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