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The downside is obvious: two needle sticks instead of one

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sudden receptor blockade in such individuals precipitates an acute withdrawal syndrome typified by agitation, vomiting, diarrhea, myalgias, and sympathetic overdrive that may necessitate inpatient management
Assali AR, Ganor A, Beigel Y, Shafer Z, Hershcovici T, Fainaru M
[ [PMID: 35807558] Aliment
