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Registry-only trials were assessed as unclear risk of bias, as critical JBI domains, such as completeness of outcome data, appropriateness of analysis, and selective reporting, cannot be evaluated without peer-reviewed results

Hyperinsulinism an inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the pancreas and congenital hyperinsulinism

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At the same time, Wegovy influences brain pathways linked to satiety, helping reduce cravings and food noise. However, it does not completely switch off hunger