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The prescribing information explains dosing, safety warnings, and contraindications in the FDA label for Wegovy tablets

This is thought to be related in part to how the medication affects appetite and fluid intake patterns as overall food consumption may decrease, some patients may also drink less, which can contribute to mild dehydration

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If there is improvement in the LVEF with this approach, the decision to rechallenge is nuanced and often part of a multidisciplinary and shared decision-making process with the patient