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The 5% Problem: The Access Gap Behind GLP-1s, Hormone Therapy, and Midlife Weight Gain What the science actually shows about menopause, metabolism, and GLP-1s - and why the biggest barrier isnt biology, but access to evidence-based care

J Postgrad Med, 62:260-263

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Therefore, almost all scientific guidelines now recommend specific treatments for patients with type 2 diabetes based on CVOTs data, namely adding to metformin a SGLT-2 inhibitor or a GLP-1RA with proven CV disease benefit in patients with type 2 diabetes and CV disease, established kidney disease, or HF [7,8,9,10]