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It was gradually found that metformin can also regulate the expression of certain genes in the gut microbiota, such as BSH genes and metalloproteins genes

doi:10.1016/0014-5793(94)01430-9

However, you can customize the dosage for patients who need something outside of whats traditionally prescribed

Competing interests MJD reported board membership and consultancy fees from Novo Nordisk, Sanofi-Aventis, Lilly, Merck, Sharp & Dohme, Boehringer Ingelheim, AstraZeneca, Servier, and Janssen

Measurements of worse eyes were used for statistical analysis, i.e., higher pRNFL thickness as a marker of oedema and lower GCL volume as a marker of neuroaxonal loss