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Description
What is GLP-1/GIP + B12, and how does it work

pmid:26757772

The exact mechanism by which metformin can contribute to lactic acidosis has yet to be fully understood [199]

As underlying mechanisms, it has been reported that GLP-1 causes renal vasodilatation, increases renal blood flow, increases glomerular filtration rate, inhibits the Na + /H + exchanger 3 in proximal tubule and decreases sodium, bicarbonate and water reabsorption [12, 14]
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