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Sitagliptin is the first of a class of drugs to be approved that mimics the actions of the dipeptidyl peptidase-4 (DPP-4) enzyme.
Phase I clinical trial results for Amgens experimental weight-loss drug, MariTide, indicate it may provide longer-lasting effects compared to existing glucagon-like peptide-1 (GLP-1) treatments such as Novo Nordisks Wegovy and EliLillys Zepbound.

Developed images revealed clear excess adiposity and high health-risk (BRI) at baseline with marked improvements, although not to within the healthy BMI (<25kg/m2) and BRI ranges at 72 weeks, observations not evident in the published report

Advocates are pushing back against Tricare's plan to end its coverage of weight-loss drugs for Tricare for Life beneficiaries by Aug
