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Unique patterns of alterations in serotonin levels in both the fasting and the postprandial state are of great interest for the pathophysiology of PBH given its role in multiple key processes in both peripheral tissues and the central nervous system linked to maintenance of normal glucose homeostasis (4145)

Additionally, undigested nutrients in the ileum activate the ileal brake, a complex mechanism influencing the digestive process and ingestive behavior [32]

Randomized trials are warranted in the future to further assess the gut mechanism after bariatric surgeries in humans

The process of adjusting the initial dosage can take up to 12 weeks
